FAPI-4 is a fibroblast activation protein (FAP) inhibitor used in cancer research.

Product information

CAS Number: 2374782-02-0

Molecular Weight: 872.91

Formula: C40H54F2N10O10

Chemical Name: 2-[4,7-bis(carboxymethyl)-10-{2-[4-(3-{[4-({2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl}carbamoyl)quinolin-6-yl]oxy}propyl)piperazin-1-yl]-2-oxoethyl}-1,4,7,10-tetraazacyclododecan-1-yl]acetic acid

Smiles: N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)C1=CC=NC2=CC=C(C=C12)OCCCN1CCN(CC1)C(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1

InChiKey: ICWDAESAANBIGG-LJAQVGFWSA-N

InChi: InChI=1S/C40H54F2N10O10/c41-40(42)21-29(22-43)52(28-40)34(53)23-45-39(61)31-4-5-44-33-3-2-30(20-32(31)33)62-19-1-6-46-15-17-51(18-16-46)35(54)24-47-7-9-48(25-36(55)56)11-13-50(27-38(59)60)14-12-49(10-8-47)26-37(57)58/h2-5,20,29H,1,6-19,21,23-28H2,(H,45,61)(H,55,56)(H,57,58)(H,59,60)/t29-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (114.56 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.